Clinical Immunology: Principles and Practice, 6th Edition

Offering unique, comprehensive coverage of both basic science and clinical scenarios, Clinical Immunology: Principles and Practice, 6th Edition, brings you up to date with every aspect of this fast-changing field. This fully revised edition provides authoritative guidance from some of the most respected global leaders in immunology in one complete, well-illustrated volume, edited by M.D. Rich, Robert R., M.D. Fleisher, Thomas A., Ph.D. Schroeder, Harry W., Jr., Ph.D. Weyand, Cornelia M., and M.D. Corry, David B.

Comprehensive Scientific and Clinical Coverage

It examines the molecular, cellular, and immunologic bases of immunologic diseases and their broader systemic implications; it also includes complete coverage of common and uncommon immunologic disorders. The book addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more.

Key Updates and Breakthroughs

Updated with all the latest immunologic research and clinical implications, including breakthrough immunotherapies and molecular-based treatment protocols, the 6th edition features:

• Extensive revisions that reflect rapidly expanding research and clinical advances, including breakthrough drug and immunotherapies such as immune checkpoint inhibitors, immunotherapies for cancer, precision medicine, and transfusion medicine.
• New chapters on COVID-19, immune responses, and the role of the immune system; immunoregulatory deficiencies; immune checkpoints; CAR T cells, including new cellular-based immunotherapy; gene therapy, including CRISPR and gene selection; and a clinically focused chapter on asthma.
• New genetics content focused on data applications and the role of genetics and genomics in immune response and immunologic disease.

Research and Clinical Topics

The text covers hot topics such as atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, and the role of microbiota in normal immune system development. Furthermore, it summarizes promising research and development anticipated over the next 5–10 years with "On the Horizon" boxes and discussions of translational research.

User-Friendly Format and Educational Tools

Features a user-friendly format with color-coded boxes highlighting critical information on Key Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic Principles. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Summary of Book Features

• Editor-in-Chief: Robert R. Rich, M.D.
• Latest Subjects: COVID-19, CAR T cells, CRISPR, and Microbiota.
• Clinical Aids: Key Concepts and Clinical Pearls boxes.
• Format: Hardcover and eBook included.